林 建 甫

Chien-Fu Jeff Lin MD., PhD.

e-mail: cflin@mail.ntpu.edu.tw

 


醫學統計與流行病學研究興趣:

Survival Analysis

Clinical Trials

Bioinformatics and Genetics Statistics

Longitudinal Data Analysis

Bayesian Analysis

Missing Data Analysis

Screening for Chronic Diseases

Health Economics and Management

 


研究主題:

2010-Present: 健保資料庫縱向資料分析與存活資料分析

2000-Present: 肺癌篩檢與存活資料分析

1995-Present: 肺癌、食道癌淋巴結分子標記,基因表現與存活分析,台北榮民總醫院

2006-2008: 國科會肺癌基因體計畫:利用功能基因體學尋找肺腺癌之治療標的, 統    計諮詢顧問 (台北榮民總醫院, 國衛院)

2005-2006: 不完全排序資料分析,國科會NSC 94-2118-M-305-002

2002-Present: 醫療選擇行為分析,台北大學

2002-2004: 健康管理流行病學與健康促進長期追蹤研究,輔仁大學

2000-2004: 骨骼肌肉腫瘤存活分析,台北榮民總醫院

1995-Present: 運動傷害流行病學與再次傷害長期追蹤分析,輔仁大學

1992-1995:  Oral hygine and chronic disease in geriatric population

      End stage renal disease and kidney transplantation

      (University of Michigan)

 


指導研究生: 

許明樹, 碩士,(2009),骨質疏鬆骨折病患服用 Alendronate 與再次骨折之關聯性

(共同指導: 梁文敏教授)

鄭奇浲, 碩士,(2009), 50歲以上髖關節骨折之歷年發生率、死亡率與手術併發症分析-以台灣人口為基礎之世代研究 (共同指導: 梁文敏教授)

趙百筠, 碩士,(2009), 不同族群肺腺癌組織微陣列晶片基因表現類別差異整合分析

鄭茹因, 碩士,(2009), 不同族群肺正常組織微陣列晶片基因表相等性整合分析

呂憶潔,碩士,(2008), 配對設計微陣列晶片基因表現相關性與類別差異性檢定

王譚景,碩士,(2008), 配對設計微陣列晶片基因表現相關性與存活分析

彭湘婷,碩士,(2007),不完全排序資料貝氏分析 (in Chinese)

古惠瑜,碩士, (2007),Bayesian Evaluation for a Combination of Generic Drugs (in English)

                                         (貝氏評估合併多種學名藥物治療)

高偵云,碩士,(2006),Multi-State Model For Daily Stock Trend (in English)

                  (多重狀態模型分析每日股價趨勢)

吳志學,碩士,(2005),Incomplete Rank Data Analysis – Likelihood Approach (in English)

李月麗,碩士,(2004),不完全排序資料四種分析方法比較 (in Chinese)

  (Compare Four Different Methods for Incomplete Rank data)

徐亭媺,碩士,(2003),Missing data analysis of ranking experiments (in English)

            


專書:

林建甫: 存活分析 ( Survival Analysis)  2008, 雙業書局.

 


博士論文:

Models for Serial Screening of Chronic Diseases.

指導教授 (advisor): Robert A. Wolfe, PhD.

 


Publication in Journals:

CB Wang, CF Jeff Lin, WM Liang, CF Cheng, YJ Chang, HC Wu, TN Wu, TH Leu,

Excess mortality after hip fracture among the elderly in Taiwan:

A nationwide population-based cohort study

Bone, 2013, September, 56(1): 147-153.

[September, 2013]

(Co-first author and responder)

 

CC Chiang, CF Jeff Lin, YH Tzeng, CK Huang, WM Chen, Liu CL.Distal linear osteotomy compared to oblique diaphyseal osteotomy in moderate to severe hallux valgus

Foot Ankle Int. 2012 Jun; 33(6):479-486.

[Jun, 2012]

 

CC Chiang, Wu HT, CF Jeff Lin, YH Tzeng, CK Huang, WM Chen, Liu CL

Analysis of initial injury radiographs of occult femoral neck fractures in elderly patients: a pilot study.

Orthopedics. 2012 May; 35(5):e621-627.

[May, 2012] http://www.healio.com/orthopedics/journals/ORTHO/%7BC21DBF09-291A-4D08-8B67-DDFC37E524F2%7D/Analysis-of-Initial-Injury-Radiographs-of-Occult-Femoral-Neck-Fractures-in-Elderly-Patients-A-Pilot-Study?full=1

 

CC Chiang, WM Chen, CF Jeff Lin, CF Chen, CK Huang, YH Tzeng, CL Liu, Comparison of a minimally invasive technique with open tension band wiring for displaced transverse patella fractures

Journal of the Chinese Medical Association, 2011, vol 74, No 7, p-316-321.

[July, 2011]

http://www.sciencedirect.com/science/article/pii/S1726490111001614

 

CC Chiang, CK Huang, WM Chen, CF Jeff Lin, YH Tseng, CL Lin,

Arthroscopically assisted percutaneous osteosynthesis of displaced transverse patellar fractures with figure-eight wiring through paired cannulated screws

Archives of Orthopaedic and Trauma Surgery, 2011, Vol 131, No 7, p949-954,

[July 2011] http://www.springerlink.com/content/r97lu8t8678k4g46/

 

WT Chia, CF Jeff Lin, LT Yeh, HK Sytwu,

A Noncontact Footpad Thickness Assay to Evaluate Rheumatoid Disease

Rheumatology International, 2010; vol 30(4):547-550. (SCI);

[Feb, 2010]

 

Chiu, FY, Lin CF,

Antibiotic-Impregnated Cement in Revision Total Knee Arthroplasty. A Prospective Cohort Study of One Hundred and Eighty-three Knees  
J Bone Joint Surg Am. 2009;91:628-633. (SCI)

[Mar 1 , 2009] http://www.ejbjs.org/cgi/content/full/91/3/628

 

WT Chia, YS Chen, CF Jeff Lin, HH Liu, BF Lin,

Difference in time to x ray with similar time to treatment decision leads to differences in waiting times of patients with hip fracture in a crowded emergency department.

Emerg. Med. J.; 2008; 25; 274-275 (SCI)

[May 1, 2008] http://emj.bmj.com/content/25/5/274.full.pdf

 

HW Wang, CT Hsueh, CF Jeff Lin, WH Hsu, LS Wang, YC Wu

Clinical Implications of Microsomal Prostaglandin E Synthase-1 Overexpression in Human Non-small Cell Lung Cancer

Annals of Surgical Oncology, vol:13(9):1224-1234, 2006 (SCI).

[Sep. 1, 2006] http://www.annalssurgicaloncology.org/cgi/content/abstract/13/9/1224

 

Lin CF, Wu JJ, Chen TS, Huang TF,

Comparison of the Insall-Salvati ratio of the patella in patients with and without an ACL tear.

Knee Surgery, Sports Traumatology, Arthroscopy, vol 13(1):8-11, 2005. (SCI).

[Jan 1, 2005] http://www.springerlink.com/openurl.asp?genre=article&id=doi:10.1007/s00167-004-0515-7

 

YC Wu, CF Jeff Lin, WH Hsu, BS Huang, MH Huang, LS Wang,

Long-term results of pathological stage I non-small cell lung cancer-validation

of using the number of totally removed lymph nodes as a staging control.

European Journal of Cardio-thoracic Surgery, vol 24(6), p994-1001, 2003 (SCI).

[December, 2003] http://ejcts.ctsnetjournals.org/

 

JY Ko, CJ Wang, CF Jeff Lin, CH Shih,

Periacetabular osteotomy through a modified Ollier transtrochanteric approach for treatment of painful dysplastic hips.

J of Bone and Joint Surgery (Am), Vol 84-A(9), p1594-1604, 2002 (SCI).

[September, 2002] http://www.ejbjs.org/

 

FY Chiu, CM Chen, CF Jeff Lin, WH Lo,

Cefuroxime-impregnated cement in primary total knee arthroplasty: a prospective, randomized study of three hundred and forty knees.

J of Bone and Joint Surgery (Am) Vol 84-A(5), p759-762, 2002 (SCI).

[May, 2002] http://www.ejbjs.org/

 

ST Wang, HL Ma, CF Jeff Lin, CL Liu, WK Yu, WH Lo,

Surgical treatment of adult idiopathic scoliosis-comparison of two instrumentations.

International Orthopaedics (SICOT), Vol 26, p207-210, 2002 (SCI).

[April, 2002] http://www.sicot.org/

 

LC Hwang, WH Lo, WM Chen, CF Jeff Lin, CK Huang, CM Chen,

Intertrochanteric fractures in adults younger than 40 years of age,

Archieves of Orthopaedic & Trauma Surgery, Vol 121 (3): p123-6, 2001 (SCI).

[March, 2001] http://link.springer.de/link/service/journals/00402/

 

F.Y. Chiu, CF Jeff Lin, CM Chen, WH Lo TY Chuang,

Cefuroxime-impregnated cement at primary total knee arhroplasty in diabetes mellitus,

J of Bone and Joint Surgery, (Br), Vol 83-B(5), p691-695, 2001 (SCI).

[May, 2001] http://www.jbjs.org.uk/

 

HT Wu, CY Chang, CF Jeff Lin, TH Chen, WM Chen,

Preoperative MR imaging assessment of osteosarcoma: a Radiological-surgical correlation,

Chinese J. Radiology Vol 26 (1): p9-16, (2001).

[January, 2001] http://www.hint.org.tw/globmed.htm

 

WL Ma, JJ Wu, CF Jeff Lin, WH Lo,

Surgical treatment of full thickness rotator cuff tear in patients younger than 40 years,

Chinese Medical Journal (Taipei), Vol 63, No 6, p452-453, 2000.

[June, 2000] http://www.bone.org.tw/as_2frame.html

 

WM Chen, TH Chen, CK Huang, CF Jeff Lin, LY Shih, WH Lo,

Treatment of high-grade primary osteosarcoma in extremities - 15-year clinical experience in VGH-Taipei,

J of Orthopaedic Surgery, R.O.C., v17, p11-16, 2000.

[January, 2000] http://www.bone.org.tw/as_2frame.html

 

TR Luan, MC Chang, CF Jeff Lin, Y Liu, WH Lo,

Percutaneous A1 pully release for trigger digit, 

Chinese Medical Journal (Taipei), Vol 62, No 1, p33-39, 1999.

[January, 1999] http://www.hint.org.tw/globmed.htm

 

CL Liu, CH Cheng, CF Jeff Lin, ST Wang, CF Wu, H Chang, WH Loo,

Isokinetic evaluation of the ankle before and  after surgical treatment of the lumbar discherniation,

Clinical Biomechanics, vol.13  Supplement, No 1. p S46-S51, 1998 (SCI).

[December, 1998] http://www.elsevier.com/wps/find/journaldescription.cws_home/30397/

 

CC Chiang, MC Chang, CF Jeff Lin, Y Liu,

Computerized Tomography in the Diagnosis of Subluxation of the Distal Radioulnar Joint,

Chinese Medical Journal (Taipei), Vol 61, No 12, p708-715, 1998.

[December, 1998] http://www.hint.org.tw/globmed.htm

 

LS Wang, HY Lin, CJ Chang, HJ Fahn, MH Huang, CF Jeff Lin,

Effects of en bloc esophagectomy on nutritional and immune status in patients with esophageal carcinoma, J of Surgical Oncology, Vol 67(2): p90-8, 1998 (SCI).

[February, 1998] http://www.wjso.com/articles/browse.asp

 

FY Chiu, CM Chen, CF Jeff Lin, WH Lo, YL Huang, TH Chen,

Closed humeral shaft fractures, a prospective evaluation of surgical treatment,

J of Trauma-Injury Infection & Critical Care, v43(6), p947-951, 1997 (SCI).

[December, 1997] http://lib.harvard.edu/e-resources/details/j/jtriicca.html

 

WM Chen, HJ Chiou, WH Lo, CK Huang, KS Lee, CF Jeff Lin, KF Tseng,

Quantitative ultrasounography to evaluate the  optimal timing of wound drain removal

following total knee arthroplasty,

J of Orthopaedic Surgery, R.O.C., v14, p1-6, Mar 1997.

[January, 1997] http://www.bone.org.tw/as_2frame.html

 

GH Hidebrandt, WJ Loesche, CF Jeff Lin, WA Bretz,

Comparison of number and type of dental function units in geriatric population

with diverse medical background,

J of Prosthetic Dentistry, v73, p 235-261, 1995 (SCI).

[March, 1995] http://www2.us.elsevierhealth.com/scripts/om.dll/serve?action=searchDB&searchDBFor=home&id=pr


 


Presentation in International Conferences :

CF Jeff Lin

Paired and Unpaired Samples in Affymetrix Microarray for Survival Analysis

presented at International CSA-JSS-KSS Joint Statistical Conference, Taiwan, 2008

 

CF Jeff Lin

Incomplete Rank Data Analysis with Multiple Imputation

presented at International Conference on Survey Research Methodology, Taiwan, 2008

 

Presentation in Conferences:

 

CF Jeff Lin, MS Hsu, TS Liu, CB Wang, YC Chang, ML Chiu, WM Liang

The association between the duration of alendronate usage and the secondary fracture prevention: a retrospective, case-control cohort study from Insurance Database in Taiwan, presented at Chinese Orthopaedics Association Annual Meeting Oct, 2012

 

CF Jeff Lin, TS Liu, CB Wang, YC Chang, ML Chiu, WM Liang

Incidence, mortality and post-operative complication of hip fracture in patients aged between 40-60 years old – a population-based cohort study, presented at Chinese Orthopaedics Association Annual Meeting Oct, 2012

 

Internal fixation versus primary bipolar hemiarthroplasty for intertrochanteric fracture among patients aged 60 or order – a population-based cohort study, presented at Chinese Orthopaedics Association Annual Meeting Oct, 2012

 

TS Liu, CF Jeff Lin, CB Wang, YC Chang, ML Chiu, WM Liang

Mortality and post-operative complication for intertrochanteric fracture of femur among patients aged less than 40 – a population-based cohort study, presented at Chinese Orthopaedics Association Annual Meeting Oct, 2012

 

MS Shu, WM Liang , CB Wang, YC Chang, ML Chiu, TS Liu, CF Jeff Lin,

Internal fixation versus primary bipolar hemiarthroplasty for intracapsular femoral neck fracture in patients aged between 60 and 80 years: a population-based study,

presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

JS Dai, WM Liang , CB Wang, YC Chang, ML Chiu, TS Liu, CF Jeff Lin,

Internal fixation versus unipolar hemiarthroplasty for femoral neck fracture in patients aged 80 and over: a population-based study, presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

CS Chiu, WM Liang , CB Wang, YC Chang, ML Chiu, TS Liu, CF Jeff Lin,

Incidence, mortality and complications of femoral neck fracture in patients aged between 20 and 60 years: a population-based study,

presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

CF Cheng, WM Liang , CB Wang, YC Chang, ML Chiu, TS Liu, CF Jeff Lin,

Internal fixation versus primary hemiarthroplasty for femoral neck fracture in patients aged 40-60: a population-based study,

presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

CF Jeff Lin, TS Liu, CB Wang, YC Chang, ML Chiu, WM Liang

Incidence, mortality and surgical complications of hip fracture in patients aged 50 or older – a population-based cohort study,

presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

CF Jeff Lin, TS Liu, CB Wang, YC Chang, ML Chiu, WM Liang

Internal fixation versus primary hemiarthroplasty for hip fracture in patients aged 60 or order – a population-based cohort study,

presented at Chinese Orthopaedics Association Annual Meeting Apr, 2012

 

CF Jeff Lin

Incomplete Rank Data Analysis with Multiple Imputation

presented at International Conference on Survey Research Methodology, Taiwan, 2008

YJ Lu and CF Jeff Lin

Paired and Unpaired Design in Class Comparisons for Affymetrix Microarray

presented at South Statistics Conference, Taiwan, 2008

TJ Wang and CF Jeff Lin

Paired and Unpaired Design in Affymetrix Microarray for Survival Analysis

presented at South Statistics Conference, Taiwan, 2008

          XT Pong and CF Jeff Lin 

          Bayesian anaysis for incomplete rank data

          presented at South Statistics Conference, Taiwan, 2007

 

          HY Gu and CF Jeff Lin

          Bayesian Evaluation for a Combination of Generic Drug

          presented at South Statistics Conference, Taiwan, 2007

TF Huang, CF Jeff Lin, JJ Wu, HL Ma, TH Chen,

Compare patella Insall-Salvati Ratio in Patients with ACL tear and without ACL tear,

presented at Chinese Orthopaedics Association Annual Meeting, 2003.

 

CF Jeff Lin and A. Wang,

A prospective study to compare college athlete sports re-injury risk after four different initial treatments, including western medicine, traditional Chinese medicine, self-management and no treatment,

presented at Chinese Orthopaedics Association Annual Meeting, 2002.

 

CF Jeff Lin,

A statistical study of papers in the Journal of Orthopedic Surgery 1995-2000,

presented at Chinese Orthopaedics Association Annual Meeting, 2001.

 

F.Y. Chiu, CF Jeff Lin, CM Chen, WH Lo TY Chuang,

Cefuroxime-impregnated cement at primary total knee arhroplasty in diabetes mellitus,

presented at Chinese Orthopaedics Association Annual Meeting, 2001.

 

JY Ko, CJ Wang, CF Jeff Lin, CH Shih,

Periacetabular osteotomy for painful dysplastic hips-using modified Olliers Approach,

presented at Chinese Orthopaedics Association Annual Meeting, 2001.

 

TW Huang, CJ Wang, CF Jeff Lin,

PCL graft angulation and translation-a cadaver study,

presented at Chinese Orthopaedics Association Annual Meeting, 2001.

 

CC Chiang, TH Chen, C.F. Jeff Lin, WH Lo, CK Huang, WM Chen,

Comparison of Total Hip replacement with Hydroxypatite Coated Implant

for Avascular Necrosis and Degenerative Osteoarthritis of the Hip,

presented at Chinese Orthopaedics Association Annual Meeting, 2000.

 

FY Chiu, CM Chen, CF Jeff Lin, WH Lo,

Cefuroxime Impregnated Cement in Primary Total Knee Arthroplasty

A Prospective randomized Study of 290 Cases,

presented at Chinese Orthopaedics Association Annual Meeting, 2000.

 

YC Wu, C.F. Jeff Lin, LS Wang, BS Huang, WH Hsu, MH Huang,

Prognostic models in stage I non-small cell lung cancer after surgery,

present at Surgical Association of ROC Annual Meeting, 2000.

 

CC Chiang, WH Lo, C.F. Jeff Lin, WM Chen, CK Huang, TH Chen,

Comparison of the Radiographic results of Hydroxyapatite-coated Femoral Components

between Younger and Elder patients,

presented at Chinese Orthopaedics Association Annual Meeting, 1999.

 

TH Chen, CF Jeff Lin, WM Chen, CK Huang, FY Chiu, JJ Wu, WH Lo,

Cementless total hip replacement short- term clinical and roentgenographic results of 405 hips,

presented at International Committee Meeting of  Asian Societe of joint reconstruction, 1998.

 

R Young, WH Lo, WM Chen, CF Jeff Lin, TH Chen, CH Huang, FY Chiu,

What are the risk factors causing patellar instability after total knee arthroplasty ?

presented at 1997 International Committee Meeting of Societe Internationale de Chirurgie Orthopaedique etde Trauma Tologie.and Chinese Orthopaedics Association Annual Meeting, 1997

 

CC Chiang, TH Chen, CF Jeff Lin, WM Chen, CK Huang, FY Chiu, JJ Wu, WH Lo,

Cementless bipolar hip prosthesis short- term clinical and roentgenographic results of 93 hips,

presented at 1997 International Committee Meeting of Societe Internationale de Chirurgie Orthopaedique etde Trauma Tologie.and Chinese Orthopaedics Association  Annual Meeting, 1997.

 

TR Luan, MC Chang, CF Jeff Lin, Y Liu, WH Lo,

Percutaneous A1 pully release,

presented at 1997 International Committee Meeting of Societe Internationale de Chirurgie Orthopaedique etde Trauma Tologie.and Chinese Orthopaedics Association Annual Meeting, 1997.

 

LJ Hwang, WH Lo, WM Chen, CF Jeff Lin, CK Huang, TH Chen,

Risk factors assessment in cemented hip arthroplasty,

presented at Chinese Orthopaedics Association Annual Meeting, 1996.

 

LJ Hwang, WH Lo, CF Jeff Lin, CK Huang, WM Chen, CM Chen,

Intertrochanteric fracture in patients younger than 40 years of age,

presented at Chinese Orthopaedics Association Annual Meeting, 1996.

 

Chen, HJ Chiou, WH Lo, CK Huang, KS Lee, CF Jeff Lin, KF Tseng,

Quantitative ultrasounography to evaluate the optimal timing of wound drain removal

following total knee arthroplasty,

presented at Chinese Orthopaedics Association Annual Meeting, 1996.

 


 Invited Speeches and Short Courses:

基礎生物醫學研究: 統計原則 (2009) 陽明大學臨床醫學研究所.

臨床試驗研究設計之考量 (Clinical Trials Design Considerations) (2009) 中華民國製藥發展協會.

醫學測量一致性與測量誤差分析 (2008) 亞洲環宇醫學編譯公司.

Paired and Unpaired Design in Affymetrix Microarray for Survival Analysis, (2009), 台北榮民總醫院

Missing Data Analysis of Ranking Experiments (2005), 台北大學.

Clinical Trials, (2004, one-day short course), 台北榮民總醫院.

Analysis of Incomplete Rank Data, (2004), 台北大學.

Design in Clinical Research, I & II (2003, two-week short course), 台北振興醫院.

Missing Data Analysis, (2003), 台北榮民總醫院.

Models for Screening of Chronic Diseases, (2002), 台北榮民總醫院.

Models for Screening of Chronic Diseases, (2002), 陽明大學.

Design and Data Analysis in Cancer Research (2002),

    An Advance in Research Works for Clinical Investigators and Oncologists, (one-day short course).

從生物統計觀點看後基因體時代生物醫學資料分析 (2001), 中山大學.